Dextromethorphan is a medication most often used as a cough suppressant in over-the-counter cold and cough medicines. It is sold in syrup, tablet, spray, and lozenge forms. It is in the morphinan class of medications with sedative, dissociative, and stimulant properties.

Molar mass: 271.4 g/mol

Formula: C18H25NO

Melting point: 111 °C (232 °F)

Trade name: Robitussin, Delsym, DM, DexAlone, Duract, others

Elimination half-life: 2–4 hours (extensive metabolizers); 24 hours (poor metabolizers)

Metabolism: Hepatic (liver) enzymes: major CYP2D6, minor CYP3A4, and minor CYP3A5

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